![]() MRM™ Algorithm Dwell time is the time spent acquiring the targeted MRM transition during each cycle. Adjust needle voltage (2000-4500 V depending on analyte characteristics, solvent, ion source temperature and nebulizer pressure). The cell acceleration voltage plays an important role for the accumulation time of ions in the collision cell. This reduces the potential method impact of adding analytes and of retention time shifts. Projects are specific to the version of Optimizer that you use to create them.ĭynamic MRM removes the requirement to resolve compounds to baseline and to create well-defined segments in the chromatogram where no compounds elute. Select Programs> Agilent> MassHunter Workstation> Optimizer for Peptides from the Windows Start menu. Select Programs> Agilent> MassHunter Workstation> Optimizer from the Windows Start menu. ![]()
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